Peter Jung

The paper develops a stochastic model to explain how neurofilament transport is accelerated at nodes of Ranvier due to increased proximity to microtubule tracks.

The paper uses a computational model to predict how bulk actin transport rates depend on axon caliber, nucleation site density, and trail length, and argues against a diffusion-based mechanism.

The paper shows that actin in axons moves via biased polymerization, not polymer-sliding, through dynamic hotspots and trails, explaining slow axonal transport.