Author

Timothy J. Colston

University of Puerto Rico-MayaguezORCID 0000-0002-1127-1207Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:database / resource· 1 Approach:statistical model· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Alex R. Van DamiD· 1 shared Alfredo Rodriguez RuiziD· 1 shared LAURA V. MARTINEZ APONTEiD· 1 shared Sean A. LockeiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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1 shared paperGenomics

Alex R. Van DamORCID

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1 paper

Recent·Most cited

The genome of the coffee bean weevil (Araecerus fasciculatus) reveals a cytochrome P450 repertoire as a convergent candidate mechanism of insect-origin caffeine detoxification

LAURA V. MARTINEZ APONTE, Alfredo Rodriguez Ruiz, Sean A. Locke, Timothy J. Colston, Alex R. Van Dam

This paper presents the first functionally annotated genome of the coffee bean weevil, identifying a unique insect-encoded P450 detoxification pathway for caffeine, distinct from bacterial mechanisms.

bioRxiv · Jun 15, 2026 · PreprintGenomics