Evolutionary BiologyProceedings of the National Academy of SciencesPeer-reviewed
The persistence and loss of hard selective sweeps amid admixture in ancient Eurasians
Mariana Harris, Ziyi Mo, Adam C. Siepel, Nandita R. Garud
This study uses a domain-adaptive neural network to detect selective sweeps in ancient Eurasian genomes, finding that hard sweeps at loci related to neuronal, reproductive, pigmentation, and signaling traits persisted despite admixture.