BioinformaticsbioRxivPreprint
Contamination of widely used databases compromises rRNA based taxonomic assignment of metagenomes and metatranscriptomes
Alastair Grant, Charli S. Davies
The paper shows that contamination of rRNA databases with LSU sequences leads to incorrect taxonomic assignments in metagenomes and metatranscriptomes, and provides a cleaned database and tool to address this issue.
DOI 10.64898/2026.07.22.739903