Site-specific phosphorylation of Ser352 drives aggregation of Tau R4 under acidosis conditions
Shachar Bressler, Carmia Blacher, Karina Abramov Harpaz, Dana Grunhaus, Stefan Rüdiger, Mattan Hurevich, Deborah E. Shalev, Yifat Miller, Assaf Friedler
The paper identifies site-specific phosphorylation of Ser352 as the molecular switch driving Tau R4 aggregation under acidosis conditions.
Chemical Science · Jan 1, 2026Peer-reviewedBiochemistry