Deconvolution of cancer methylation patterns determines that altered methylation in cancer is dominated by a non-disease associated proliferation signal
H. Lalchungnunga, Hande Atasoy, Ed C. Schwalbe, Chris M. Bacon, Gordon R. Strathdee
The paper deconvolves cancer methylation patterns to show that most methylation changes in B-cell cancers are proliferation-driven, not disease-specific, and identifies SLC22A15 as a novel tumour suppressor.
British Journal of Cancer · Oct 31, 2025Peer-reviewedCancer Biology