Mechanistic computational modeling of monospecific and bispecific antibodies targeting interleukin-6/8 receptors
Christina M.P. Ray, Yang Hui-lin, Jamie B. Spangler, Feilim Mac Gabhann
The paper develops a computational model to analyze how bispecific antibodies interact with IL-6 and IL-8 receptors, showing how binding dynamics influence therapeutic efficacy.
PLoS Computational Biology · Jun 7, 2024Peer-reviewedSystems Biology