Norepinephrine and glucocorticoids modulate chronic unpredictable stress-induced increase in the type 2 CRF and glucocorticoid receptors in brain structures related to the HPA axis activation.
Marília Brinati Malta, Joelcimar Martins, Leonardo Santana Novaes, Nilton Barreto dos Santos, Luciane V. Sita, Rosana Camarini, Cristóforo Scavone, Jackson Cioni Bittencourt, Carolina Demarchi Munhoz
This paper investigates how chronic unpredictable stress affects CRF and glucocorticoid receptors in brain regions related to the HPA axis and finds that stress increases CRF2 and GR levels in specific brain areas.
Molecular Neurobiology · Jul 2, 2021Peer-reviewedNeuroscience