Molecular BiologyCellPeer-reviewed
RNA G-quadruplexes forming scaffolds for alpha-synuclein aggregation lead to progressive neurodegeneration
Kazuya Matsuo, Sefan Asamitsu, Kohei Maeda…·Yasushi Yabuki
This study shows RNA G-quadruplexes scaffold alpha-synuclein aggregation, leading to neurodegeneration, and demonstrates that inhibiting this process can alleviate symptoms in a mouse model.
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