Author

Zhonghuang Wang

Chinese Academy of SciencesORCID 0000-0002-1268-883XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 3

Signature Assays, Organisms & Methods

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Approach:large language model· 2 Research Focus:benchmarking· 1 Research Focus:database / resource· 1 Organism:human· 1 Assay:imaging· 1 Research Focus:protein design· 1 Assay:protein sequence· 1 Research Focus:software / tool· 1

Frequent Co-Authors

Bing HeiD· 2 shared Jianhua YaoiD· 2 shared Wenming ZhaoiD· 2 shared Yanling SuniD· 2 shared Anke WangiD· 1 shared Bixia TangiD· 1 shared Bo YuaniD· 1 shared Chenchen QiniD· 1 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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2 shared papersBioinformatics

Bing HeORCID

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Author profile →

3 papers

Recent·Most cited

An Artificial Intelligence Model for Longitudinal Assessment of TCR Repertoires in SARS-CoV-2 Vaccine Recipients

Zhonghuang Wang, Yu Shan Zhao, Xiao Xiao, Bing He, Yanling Sun, Shan Xiong, Chenchen Qin, Zhipeng Zhou, Lianpeng Chang, Jing Bai, Wenming Zhao, Wenhua Liang, Jianhua Yao

The paper develops a large language model to predict SARS-CoV-2-specific TCRs and shows their correlation with antibody levels post-vaccination.

bioRxiv · Sep 18, 2026 · PreprintBioinformatics

De novo generation of T-cell receptors with desired epitope-binding property by leveraging a pre-trained large language model

Jiannan Yang, Bing He, Yu Zhao, Feng Jiang, Zhonghuang Wang, Yixin Guo, Zhimeng Xu, Bo Yuan, Jiangning Song, Qingpeng Zhang, Jianhua Yao

The paper introduces ERTransformer, a large language model that generates T-cell receptors with desired epitope-binding properties, showing high functional similarity to natural TCRs.

bioRxiv · Oct 18, 2023 · PreprintBioinformatics

OBIA: An Open Biomedical Imaging Archive

Enhui Jin, Dongli Zhao, Gangao Wu, Junwei Zhu, Zhonghuang Wang, Zhiyao Wei, Sisi Zhang, Anke Wang, Bixia Tang, Xu Chen, Yanling Sun, Zhe Zhang, Wenming Zhao, Yuanguang Meng

OBIA is a biomedical imaging archive that stores and provides access to imaging and clinical data from 937 individuals across multiple modalities and anatomical sites.

Genomics Proteomics & Bioinformatics · Oct 1, 2023Peer-reviewedBioinformatics