Causal Network Inference from Gene Transcriptional Time Series Response to Glucocorticoids
Jonathan Lu, Bianca Dumitrascu, Ian C. McDowell, Brian Jo, Alejandro Barrera, Linda K. Hong, Sarah M. Leichter, Timothy E. Reddy, Barbara Elizabeth Engelhardt
The paper introduces BETS, a statistical framework for inferring gene regulatory networks from transcriptional time series data, and validates it using glucocorticoid response data and external sources.
PLoS Computational Biology · Jan 29, 2021Peer-reviewedBioinformatics