Author

Sarah M. Leichter

Duke UniversityORCID 0000-0001-7572-3375Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:Arabidopsis· 1 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Alejandro BarreraiD· 1 shared Barbara Elizabeth EngelhardtiD· 1 shared Bianca DumitrascuiD· 1 shared Brian JoiD· 1 shared Dean SandersiD· 1 shared Ian C. McDowelliD· 1 shared Jia GweeiD· 1 shared Jian FangiD· 1 shared

Activity by Year

2021-2024 · peak 1/yr

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10 top collaborators · 20 mutual co-author links

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1 shared paperBioinformatics

Alejandro BarreraORCID

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2 papers

Recent·Most cited

Plant BiologyScience AdvancesPeer-reviewedNov 6, 2024

Substrate specificity and protein stability drive the divergence of plant-specific DNA methyltransferases

Jianjun Jiang, Jia Gwee, Jian Fang…·Xuehua Zhong

This study investigates how CMT2 and CMT3 diverge in substrate specificity and protein stability, revealing evolutionary mechanisms of DNA methylation in plants.

28 citations

ArabidopsisDNA methylation

𝕏 PostBluesky

BioinformaticsPLoS Computational BiologyPeer-reviewedJan 29, 2021

Causal Network Inference from Gene Transcriptional Time Series Response to Glucocorticoids

Jonathan Lu, Bianca Dumitrascu, Ian C. McDowell…·Barbara Elizabeth Engelhardt

The paper introduces BETS, a statistical framework for inferring gene regulatory networks from transcriptional time series data, and validates it using glucocorticoid response data and external sources.

35 citations

humanbulk RNA-seq

𝕏 PostBluesky