Nerve injury inhibits Oprd1 and Cnr1 transcription through REST in primary sensory neurons
Ashok Subedi, Asieh Etemad, Aadhya Tiwari, Yuying Huang, Biji Chatterjee, Samantha M. McLeod, Yungang Lu, DiAngelo Gonzalez, Krishna Kanta Ghosh, Mario Sirito, Sanjay Kumar Singh, Elisa Ruiz, Sandra L. Grimm, Cristian Coarfa, Hui‐Lin Pan, Sadhan Majumder
This study shows that nerve injury represses Oprd1 and Cnr1 transcription via REST in primary sensory neurons, suggesting REST as a therapeutic target for neuropathic pain.
Scientific Reports · Nov 4, 2024Peer-reviewedNeuroscience