Systems BiologyPLoS Computational BiologyPeer-reviewed
Dynamic Modeling of Cell Cycle Arrest Through Integrated Single-Cell and Mathematical Modelling Approaches
Javiera Cortés‐Ríos, María Rodriguez-Fernández, Peter Karl Sorger, Fabian Fröhlich
The paper develops a framework to integrate multiplexed immunofluorescence data with mathematical models to study cell cycle dynamics and arrest, validated on MCF-10A cells exposed to arresting agents.