Using Transcriptional Signatures to Find Cancer Drivers with LURE
David Haan, Ruikang Tao, Verena Friedl, Ioannis N. Anastopoulos, Christopher K. Wong, Alana S. Weinstein, Joshua M. Stuart
The paper introduces LURE, a semi-supervised method to predict cancer drivers using gene expression signatures, and applies it to TCGA data to find new associations with known mutation events.
Pacific Symposium on Biocomputing (PSB) · Nov 27, 2019Peer-reviewedSystems Biology