Author

Verena Friedl

University of California, Santa CruzORCID 0000-0002-7247-6038Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Assay:DNA methylation· 1

Frequent Co-Authors

David HaaniD· 2 shared Aaron Scott· 1 shared Adriana PiteaiD· 1 shared Alana S. WeinsteiniD· 1 shared Albert Nguyen· 1 shared Anna BergamaschiiD· 1 shared Bill Gibb· 1 shared Carolina Fraire· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

David HaanORCID

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2 papers

Recent·Most cited

Validation of a Pancreatic Cancer Detection Test in New-Onset Diabetes Using Cell-Free DNA 5-Hydroxymethylation Signatures

David Haan, Anna Bergamaschi, Gulfem Dilek Guler, Verena Friedl, Yuhong Ning, Roman E. Reggiardo, Michael Kesling, Micah Collins, Bill Gibb, Adriana Pitea, Kyle Hazen, Steve Bates, Michael Antoine, Carolina Fraire, Vanessa Lopez, , Samuel Levy

This paper validates a pancreatic cancer detection test using 5-hydroxymethylation signatures in cell-free DNA from patients with new-onset diabetes, showing high specificity and moderate sensitivity.

medRxiv · Dec 27, 2021 · PreprintGenetic & Genomic Medicine

Using Transcriptional Signatures to Find Cancer Drivers with LURE

David Haan, Ruikang Tao, Verena Friedl, Ioannis N. Anastopoulos, Christopher K. Wong, Alana S. Weinstein, Joshua M. Stuart

The paper introduces LURE, a semi-supervised method to predict cancer drivers using gene expression signatures, and applies it to TCGA data to find new associations with known mutation events.

Pacific Symposium on Biocomputing (PSB) · Nov 27, 2019Peer-reviewedSystems Biology