Guillem París

This study evaluates the reproducibility and reliability of free-water-corrected diffusion tensor imaging (DTI) in healthy human brain white matter across different acquisition settings and correction methods.

This study shows that free-water volume fraction in white matter increases non-linearly with age, particularly after 60, with region-specific variations and reduced variability when using FW-compensated MR signals.

The paper introduces a method to estimate brain diffusion anisotropy using only 3 gradient directions, showing it works but with increased data variability and metric subestimation.