Evaluation of the causal effects of blood lipid levels on gout with summary level GWAS data: two-sample Mendelian randomization and mediation analysis
Xinghao Yu, Ting Wang, Shuiping Huang, Ping Zeng
This paper uses Mendelian randomization and mediation analysis to evaluate the causal effects of blood lipid levels on gout using summary-level GWAS data, finding that HDL and TG influence gout risk through serum urate.
Journal of Human Genetics · Oct 25, 2020Peer-reviewedGenetic & Genomic Medicine