Xinghao Yu

This paper uses Mendelian randomization and mediation analysis to evaluate the causal effects of blood lipid levels on gout using summary-level GWAS data, finding that HDL and TG influence gout risk through serum urate.

This study finds an inverse association between low birth weight and chronic kidney disease in observational studies but no causal link using Mendelian randomization.

This study uses genetic methods to assess if higher BMI causes amyotrophic lateral sclerosis, finding no causal link.

This paper introduces JMAP, a model averaging method for genetic risk prediction that integrates pathway information, showing improved accuracy over existing methods in simulations and real cancer datasets.

The paper investigates TP53 intronic half-sites and their potential role in p53 regulation across multiple genes.