Gerald J. Sun

An artificial intelligence-based model for prediction of Clonal Hematopoiesis mutants in cell-free DNA samples

The paper presents a machine learning framework to classify variants in cell-free DNA as clonal hematopoiesis or tumor origin, achieving better classification rates than existing methods.

Optimized data representation and convolutional neural network model for predicting tumor purity

Deep Purity (DePuty) uses convolutional neural networks to predict tumor purity from SNP-based copy number and minor allele frequency data without matched normals, outperforming existing methods with fewer samples.