An artificial intelligence-based model for prediction of Clonal Hematopoiesis mutants in cell-free DNA samples
Gustavo Arango-Argoty, Marzieh Haghighi, Gerald J. Sun, Aleksandra A. Markovets, J. Carl Barrett, Zhongwu Lai, Etai Jacob
The paper presents a machine learning framework to classify variants in cell-free DNA as clonal hematopoiesis or tumor origin, achieving better classification rates than existing methods.
bioRxiv · Dec 11, 2024 · PreprintBioinformatics