Systems BiologyPLoS Computational BiologyPeer-reviewed
Evaluating the Limitations of Bayesian Metabolic Control Analysis
Janis Shin, James M. Carothers, Herbert M. Sauro
This study evaluates Bayesian Metabolic Control Analysis (BMCA) using synthetic networks, finding it requires flux and enzyme data for accurate predictions and fails to reliably infer elasticity values and allosteric regulation.