Author

Joao C. Guimaraes

QB3ORCID 0000-0002-1664-472XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Assay:DNA methylation· 1 Organism:E. coli· 1 Approach:experimental assay· 1 Assay:Ribo-seq· 1 Approach:statistical model· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Adam P. ArkiniD· 2 shared Guillaume CambrayiD· 2 shared

Activity by Year

2017-2018 · peak 1/yr

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2 top collaborators · 1 mutual co-author link

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2 shared papersSynthetic Biology

Adam P. ArkinORCID

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2 papers

Recent·Most cited

Synthetic BiologyNature BiotechnologyPeer-reviewedSep 24, 2018

Massive Phenotypic Measurements Reveal Complex Physiological Consequences Of Differential Translation Efficacies

Guillaume Cambray, Joao C. Guimaraes, Adam P. Arkin

The paper investigates the physiological consequences of differential translation efficacies by analyzing protein production, transcript abundance, and ribosome dynamics across 244,000 sequence variants.

235 citationstop 1%

Ribo-seqstatistical model

Synthetic BiologybioRxivPreprintOct 25, 2017

Massive Factorial Design Untangles Coding Sequences Determinants Of Translation Efficacy

Guillaume Cambray, Joao C. Guimaraes, Adam P. Arkin

The paper uses synthetic DNA design to analyze translation determinants in E. coli, finding mRNA structures have dominant effects over codon composition.

2 citations

E. coliDNA methylation