A Framework for Integrating Directed and Undirected Annotations to Build Explanatory Models of cis-eQTL Data.
David Lamparter, Rajat Bhatnagar, Katja Hebestreit, T. Grant Belgard, Alice Zhang, Victor Hanson-Smith
This paper introduces BAGEA, a Bayesian framework for analyzing cis-eQTL data using genomic annotations, showing it can predict up to 5% of expression variance for top-effect genes.
PLoS Computational Biology · Jun 9, 2020Peer-reviewedGenetics