The sensor of the bacterial histidine kinase CpxA is a novel dimer of extracytoplasmic Per-ARNT-Sim (PAS) domains
Timothy H. S. Cho, Cameron Murray, Roxana Malpica, Rodrigo Margain Quevedo, Gina L. Thede, Jun Lu, Ross A. Edwards, J. N. Mark Glover, Tracy L. Raivio
The paper reports the structure of the CpxA sensor domain as a novel dimer of PAS domains and shows how dimer interactions regulate activation.
Journal of Biological Chemistry · Apr 4, 2024Peer-reviewedMolecular Biology