Doan Bui

Biologically Informed Multi-Omics Integration Reveals Clinically Meaningful Patient Representations in Acute Myeloid Leukemia

This paper introduces SurvMOCA-GNN, a multi-omics integration framework that improves patient stratification in AML by incorporating biological networks and clinical data.

Single-cell RNA editing defines clinically relevant cellular states in chronic myelomonocytic leukemia

This study identifies RNA editing-defined cellular states in CMML that correlate with clinical outcomes and therapeutic response.

Disease Stage- and Risk-Associated RNA Editing Signatures in Acute Myeloid Leukemia and Their Utility for Peripheral Blood-Based Assessment

The paper identifies RNA editing signatures associated with AML disease stage and risk, showing their potential for peripheral blood-based disease assessment.

Multiscale RNA editing analysis reveals cell type specific regulatory programs across disease states in acute myeloid leukemia

The paper identifies cell type-specific RNA editing patterns in AML across disease states using single-cell and pseudo-bulk analyses, revealing condition-specific regulatory programs.

Discovery of miRNA & RNA Biomarkers for Risk Stratification in Acute Myeloid Leukemia with Multi-Cohort Validation

The paper identifies gene and miRNA biomarkers for AML risk stratification using PCA and SVM, validated across cohorts with high AUCs and regulatory insights.