Anne E. Kwitek

Multiscale RNA editing analysis reveals cell type specific regulatory programs across disease states in acute myeloid leukemia

The paper identifies cell type-specific RNA editing patterns in AML across disease states using single-cell and pseudo-bulk analyses, revealing condition-specific regulatory programs.

A revamped rat reference genome improves the discovery of genetic diversity in laboratory rats

The paper presents an improved rat reference genome, mRatBN7.2, which enhances genomic, transcriptomic, and proteomics data mapping and identifies millions of genetic variations across rat strains.

Updates to the Alliance of Genome Resources Central Infrastructure

The paper updates the Alliance of Genome Resources' central infrastructure, adding tools and enhancing data management and curation capabilities.

NECo: A node embedding algorithm for multiplex heterogeneous networks

NECo is a node embedding algorithm for multiplex heterogeneous networks that outperforms existing methods in classifying hypertension-related genes using rat disease models.

Genome variation and conserved regulation identify genomic regions responsible for strain specific phenotypes in rat

The paper identifies strain-specific genomic regions associated with metabolic syndrome in rats by integrating genomic variation and regulatory conservation.