Author

Michelangelo Fiorentino

IRCCS Azienda Ospedliero-Universitaria di Bologna Policlinico di Sant'OrsolaORCID 0000-0002-1749-150XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Organism:human· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Alessandra MorselliiD· 1 shared Andrea ArdizzoniiD· 1 shared Andrea De GiglioiD· 1 shared Arianna PalladiniiD· 1 shared Balázs GyőrffyiD· 1 shared Boobash Raj SelvaduraiiD· 1 shared Chiara Miroglio· 1 shared Cinzia Girone· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Alessandra MorselliORCID

Mutual co-authors in cluster

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1 paper

Recent·Most cited

Neuroendocrine-like/EMT dedifferentiation mediates resistance to EGFR inhibitors via the NRG1/HER3 axis

Alessandra Morselli, Chiara Miroglio, William Jayasekara Kothalawala, Idan Lahat, Donatella Romaniello, Cinzia Girone, Francesca Ambrosi, Boobash Raj Selvadurai, Suvendu Giri, Michela Sgarzi, Martina Mazzeschi, Sabrina Valente, Andrea De Giglio, Gianandrea Pasquinelli, Arianna Palladini, , Mattia Lauriola

The paper identifies NRG1/HER3 axis activation via NE-like/EMT dedifferentiation as a mechanism of EGFR inhibitor resistance in NSCLC and shows that combining EGFR inhibition with NRG1 neutralization can eradicate tumors.

bioRxiv · May 13, 2026 · PreprintCancer Biology