Rubisco is slow across the tree of life
Benoit de Pins, Cyril Malbranke, Jagoda Jabłońska, Assaf Shmuel, Itai Sharon, Anne‐Florence Bitbol, Oliver Mueller‐Cajar, Εlad Noor, Ron Milo
The paper characterizes over 250 Rubisco variants from bacteria and archaea, showing they rarely exceed 30 reactions per second at 30°C and predicting rates for all sequenced variants using machine learning.
Proceedings of the National Academy of Sciences · Nov 17, 2025Peer-reviewedSystems Biology