Juan Manuel Pedraza

Mechanisms of Cell Size Regulation in Slow-Growing Escherichia coli Cells: Discriminating Models Beyond the Adder

The paper investigates size regulation mechanisms in slow-growing E. coli cells, finding that different models explain size control under varying media conditions.

The role of division stochasticity on the robustness of bacterial size dynamics

This study investigates how stochasticity in bacterial division affects homeostasis, finding that noise in septum position and growth rate dampens oscillations in cell size dynamics.

Cell size regulation and proliferation fluctuations in single-cell derived colonies

The paper develops a framework to model cell size regulation and proliferation dynamics in single-cell-derived colonies, showing that fluctuations in cell number decrease over time in size-dependent models compared to size-independent models.

PyEcoLib: a python library for simulating E. coli stochastic size dynamics

PyEcoLib simulates E. coli stochastic size dynamics by modeling division as a jump process linked to cell size and continuous growth.

Noise signature in added size suggests bacteria target a commitment size to enable division

The paper analyzes bacterial cell size data to show that a commitment size model better explains both mean and fluctuation profiles than degradation-based models.

Division stochasticity can be transmitted to protein expression through chromosome replication

This study shows division stochasticity can transmit to protein expression through chromosome replication, but only when replication is occurring.

Stochasticity in bacterial division control: Preliminary consequences for protein concentration

The paper models bacterial cell size dynamics and protein production strategies to predict correlations between protein concentration and cell size.