Author

Ruth Fabian‐Fine

Saint Michael's CollegeORCID 0000-0002-1809-8291Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Organism:human· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Assay:proteomics· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Adam L. WeaveriD· 3 shared Abigail E Whitley· 2 shared Abigail G. Roman· 2 shared Calum J. Reding· 2 shared Chloe M. Paul· 2 shared Kyleena J. Lathram· 2 shared Luwago K. Kipingi· 2 shared Lydia A. Kragh· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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3 shared papersNeuroscience

Adam L. WeaverORCID

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Author profile →

3 papers

Recent·Most cited

Giant spider neurons uncover a myelin-derived waste-internalizing canal system that fails in neurodegeneration

Ruth Fabian‐Fine, Sondre M. Brännare-Gran, Maya N Clough, Tyler A DeBoer, Isabella DelVecchio, Matthew D Devers, Julie A. Dragon, Heather E. Driscoll, Zavier F Fuller, Keely M Hendricks, Alexander M Huesgen, Isabella C Joly, Landon G Kinal, Luwago K. Kipingi, Kyleena J. Lathram, , Emily Curd

The paper describes a glial canal system in spider neurons that removes waste via aquaporin4 and links its failure to neurodegeneration in spiders and mammals.

bioRxiv · Feb 18, 2026 · PreprintNeuroscience

Uncovering the invisible giant: Amyloid β plaques and their proposed association with waste removal in Alzheimer-affected human hippocampus

Ruth Fabian‐Fine, Abigail G. Roman, Melanie J. Winters, Kyleena J. Lathram, Carly H. Bennett, Luwago K. Kipingi, Sondre M. Brännare-Gran, Abigail E Whitley, Chloe M. Paul, Lydia M. Altman, Ian C. Carrillo, Finn M. Joyce, Lydia A. Kragh, Theodore J. McKnight, Calum J. Reding, , Adam L. Weaver

The paper investigates the role of tanycytes and their organelles in waste removal in Alzheimer's hippocampus, linking Aβ and tau to structural roles in receptacle formation and disease pathology.

bioRxiv · Jun 1, 2025 · PreprintNeuroscience

Alzheimer Disease--The proposed role of tanycytes in the formation of tau tangles and amyloid beta plaques in human brain

Ruth Fabian‐Fine, Abigail G. Roman, Adam L. Weaver

The paper investigates the role of tanycytes in forming tau tangles and amyloid beta plaques in Alzheimer's disease by analyzing their structural and molecular characteristics.

bioRxiv · Apr 8, 2025 · PreprintNeuroscience