Seeding Activity of Skin Misfolded Tau as a Novel Biomarker for Tauopathies
Zerui Wang, Ling Wu, Maria Gerasimenko, Tricia Gilliland, Zahid Syed Ali Shah, Steven A. Gunzler, Vincenzo Angelo Donadio, Rocco Liguori, Bin Xu, Wen‐Quan Zou
This study demonstrates that skin misfolded tau has prion-like seeding activity, which can be measured to differentiate tauopathies from normal controls with high sensitivity and specificity.
bioRxiv · Sep 7, 2023 · PreprintNeuroscience