An "invisible" ubiquitin conformation is required for efficient phosphorylation by PINK1
Christina Gladkova, Alexander F. Schubert, Jane L. Wagstaff, Jonathan N. Pruneda, Stefan M.V. Freund, David Komander
The paper shows that an 'invisible' conformation of ubiquitin enhances its phosphorylation by PINK1 through a dynamic equilibrium involving the Ser65 loop.
The EMBO Journal · Nov 13, 2017Peer-reviewedMolecular Biology