PhysiologybioRxivPreprint
Primary cilia coordinate c-KIT signaling induced proliferation in alpha cells
Ganga Deshar, Mariam G. Aslanyan, Gaurav D. Diwan…·Jakob Grunnet Knudsen
The paper identifies primary cilia as a signaling platform for c-KIT in pancreatic alpha cells, showing that c-KIT signaling via SCF promotes proliferation and may contribute to hyperglucagonemia in obesity and diabetes.