Glioblastoma-natural killer cell crosstalk: insights from dynamic spheroid models reveal the importance of secreted cytokines and the CD155 axis
Anamarija Habič, Tina Kolenc Milavec, Pia Žižek, Špela Kladnik, Bernarda Majc, Emanuela Senjor, Milica Perišić Nanut, Andrej Porčnik, Borut Prestor, Urban Švajger, Metka Novak, Barbara Breznik
This study uses dynamic 3D GB spheroids to investigate NK cell-GB crosstalk, identifying cytokine secretion and the CD155 axis as key factors in NK cell cytotoxicity against GB stem-like cells.
Cell Communication and Signaling · Mar 30, 2026Peer-reviewedCancer Biology