BioinformaticsGenome biologyPeer-reviewed
Unlocking biological insight from single-cell data with an interpretable dual-stream foundation model
Honglie Guo, Qinghang Cui, Xiang Zhang…·Shunfang Wang
This paper introduces scDMC, a dual-stream foundation model for single-cell data that improves representation learning and achieves state-of-the-art results in cell annotation, clustering, and integration.
DOI 10.1186/s13059-026-04193-w