Author

Yi Xie

National University of SingaporeORCID 0000-0002-1938-4089Unclaimed ORCID profile · follow to get notified of new preprints

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Yi Xie5 papers · Scripps Research Institute

Biology Disciplines

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Bioinformatics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:scRNA-seq· 2 Approach:benchmark study· 1 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Approach:statistical model· 1

Frequent Co-Authors

Enrico G. PetrettoiD· 2 shared Ahmad bin Mohamed LajamiD· 1 shared Andrea Hsiu Ling LowiD· 1 shared Huimei CheniD· 1 shared Jacques V. BehmoarasiD· 1 shared Jianfei YangiD· 1 shared John F. OuyangiD· 1 shared Salvatore AlbaniiD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

9 top collaborators · 24 mutual co-author links

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2 shared papersBioinformatics

Enrico G. PetrettoORCID

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2 papers

Recent·Most cited

scPanel: A tool for automatic identification of sparse gene panels for generalizable patient classification using scRNA-seq datasets

Yi Xie, Jianfei Yang, John F. Ouyang, Enrico G. Petretto

scPanel identifies a minimal gene panel for patient classification from scRNA-seq data, achieving high accuracy with fewer than 20 genes across multiple datasets.

Briefings in Bioinformatics · Sep 12, 2024Peer-reviewedBioinformatics

Comparative analysis of single-cell RNA sequencing methods with and without sample multiplexing

Yi Xie, Huimei Chen, Vasuki Ranjani Chellamuthu, Ahmad bin Mohamed Lajam, Salvatore Albani, Andrea Hsiu Ling Low, Enrico G. Petretto, Jacques V. Behmoaras

This study compares scRNA-seq methods with and without sample multiplexing, showing Parse detects rare cell types better despite lower efficiency, while 10X has platform-specific gene length and GC content distributions.

International Journal of Molecular Sciences · Mar 29, 2024Peer-reviewedGenomics