Comparative analysis of single-cell RNA sequencing methods with and without sample multiplexing
Yi Xie, Huimei Chen, Vasuki Ranjani Chellamuthu, Ahmad bin Mohamed Lajam, Salvatore Albani, Andrea Hsiu Ling Low, Enrico G. Petretto, Jacques V. Behmoaras
This study compares scRNA-seq methods with and without sample multiplexing, showing Parse detects rare cell types better despite lower efficiency, while 10X has platform-specific gene length and GC content distributions.
International Journal of Molecular Sciences · Mar 29, 2024Peer-reviewedGenomics