Mehreen R. Mughal

This study presents the first whole genome sequence data and genome-wide association study in a Malagasy cohort, uncovering novel body composition associations and highlighting the importance of diverse populations in genomic research.

This paper derives unbiased estimators for F- and D-statistics to reduce bias from related or inbred individuals in population genetic analyses.

The paper presents a nuclear genome sequence of the extinct koala lemur Megaladapis edwardsi and compares it with extant lemurs and non-lemur vertebrates to resolve phylogenetic relationships and evolutionary adaptations.

The paper introduces SURFDAWave, a method to identify regions of positive selection by analyzing functional data derived from genomic diversity measures, and applies it to human data to detect adaptive introgression and predict selection parameters.