Author

Samarendra Kumar Singh

Banaras Hindu UniversityORCID 0000-0002-2001-0025Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2 Biochemistry· 1 Bioinformatics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 5 Approach:statistical model· 3 Research Focus:differential expression· 2 Assay:protein structure· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Approach:deep learning· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Garima SinghiD· 3 shared Gajender SinghiD· 2 shared Vinay Kumar SinghiD· 2 shared Abhinetra Jagdish Bhopale· 1 shared Aditi GangopadhyayiD· 1 shared Anil Kumar ViD· 1 shared Deepanshu Aul· 1 shared Kumud TiwariiD· 1 shared

Activity by Year

2022-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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3 shared papersCancer Biology

Garima SinghORCID

Mutual co-authors in cluster

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5 papers

Recent·Most cited

Urinary Exosomal miRNA Profiling Reveals Sensitive Non-Invasive Diagnosis of Bladder Cancer

Garima Singh, Anil Kumar V, Lalit Kumar, Neelu Mishra, Shristy Bhattacharjee, Kunal Yadav, Yashasvi Singh, Ujwal Kumar, Sameer Trivedi, Samarendra Kumar Singh

This study identifies miRNAs in urine as non-invasive biomarkers for bladder cancer detection with high sensitivity and specificity.

bioRxiv · Oct 9, 2025 · PreprintCancer Biology

Mapping the miRNA Landscape of Gallbladder Cancer: Genome-Wide Insights and Functional Implications

Sonika Kumkari Sharma, Garima Singh, Simran Mathur, Deepanshu Aul, Puneet Gupta, Satyendra Kumar Tiwary, Vinay Kumar Singh, Samarendra Kumar Singh

This study identifies 388 differentially expressed miRNAs in gallbladder cancer, revealing their roles in tumor progression and highlighting miR-17~92 as a potential therapeutic target.

bioRxiv · Sep 29, 2025 · PreprintCancer Biology

Structural Characterization of DNA Binding Domain of Essential Mammalian Protein TTF 1

Gajender Singh, Abhinetra Jagdish Bhopale, Saloni Khatri, Prashant Prakash, Rajnish Kumar, Sukh Mahendra Singh, Samarendra Kumar Singh

This study characterizes the DNA-binding Myb domain of TTF1 using computational modeling and experimental validation, confirming its predominantly helical structure.

Bioscience Reports · Aug 1, 2024Peer-reviewedBiochemistry

Ab initio modelling of an essential mammalian protein: Transcription Termination Factor 1 (TTF1)

Kumud Tiwari, Aditi Gangopadhyay, Gajender Singh, Vinay Kumar Singh, Samarendra Kumar Singh

This study constructs the complete structure of human TTF1 using ab initio modelling and molecular dynamics simulations, identifying two residue clusters critical for structural stability.

Journal of Biomolecular Structure and Dynamics · Aug 10, 2022Peer-reviewedBioinformatics

miR-34a negatively regulates cell cycle factor Cdt2/DTL in HPV infected Cervical Cancer Cells

Garima Singh, Sonika Kumari Sharma, Samarendra Kumar Singh

This study shows miR-34a regulates Cdt2/DTL by targeting HPV E6 in cervical cancer cells, leading to reduced proliferation and increased stability of oncosuppressors.

BMC Cancer · Jul 15, 2022Peer-reviewedMolecular Biology