Adenovirus-mediated expression of SIK1 improves hepatic glucose and lipid metabolism in type 2 diabetes mellitus rats
Daofei Song, Lei Yin, Chang Wang, Xiuying Wen
This study shows that overexpressing SIK1 in T2DM rats improves glucose and lipid metabolism by suppressing gluconeogenesis and lipogenesis through specific signaling pathways.
PLoS ONE · Jun 24, 2019Peer-reviewedMolecular Biology