Fus depleted oligodendrocytes reduce neuronal damage and attenuate AD progression in the AppNL-G-F mouse
Te-Hsuan Tung, Sudhagar Babu, Xiangting Tang, Alec Sciutto, Micah A. Romer, Prathima Racha, Victoria M. Fiesler, Adrita Saha, Takashi Saito, Takaomi C. Saido, Judith B. Grinspan, Hansruedi Mathys, Takashi D.Y. Kozai, Franca Cambi
The paper shows that enhancing oligodendrocyte function in a mouse model of Alzheimer's Disease reduces neuronal damage and slows disease progression.
bioRxiv · Nov 24, 2025 · PreprintNeuroscience