Correlation of myeloid-derived suppressor cell expansion with upregulated transposable elements in severe COVID-19 unveiled in single-cell RNA sequencing reanalysis
Mitra Farahmandnejad, Pouria Mosaddeghi, Mohammadreza Dorvash, Amirhossein Sakhteman, Pouya Faridi, Manica Negahdaripour
This study reanalyzes single-cell RNA sequencing data to show that myeloid-derived suppressor cells in severe COVID-19 patients exhibit upregulated transposable elements, potentially enhancing their suppressive function.
Biomedicines · Jan 29, 2024Peer-reviewedSystems Biology