Angel E. Ibarra

12-plex DiLeu enables robust quantification of the feeding neuropeptidome

This paper uses 12-plex DiLeu labeling to quantitatively analyze the feeding neuropeptidome across multiple tissues and timepoints in Cancer borealis, revealing distinct regulatory patterns and functional specificity of peptide variants.

Bridging genomes and peptidomes: hybrid sequencing reveals conserved bioactive peptides in crustaceans

The paper develops a hybrid sequencing platform to identify endogenous peptides in crustaceans, revealing novel peptides and conserved homologies across species.

HILIC-Enabled Mass Spectrometric Discovery of Novel Endogenous and Glycosylated Neuropeptides in the American Lobster Nervous System

This study identifies 154 endogenous neuropeptides and 24 glycosylated neuropeptides in the American lobster using HILIC and EThcD mass spectrometry.

Unlocking the Neuropeptidome using a Novel Endogenous Peptidomics Framework

The paper introduces a novel peptidomics framework, EndoGenius, paired with DIA-NN, to identify neuropeptides in Cancer borealis with a 100-fold increase in detection.