Timed Notch Inhibition drives Photoreceptor fate specification in Human Retinal Organoids
Shereen Chew, Cassandra Martinez, Kathleen R. Chirco, Sangeetha Kandoi, Deepak A. Lamba
The paper inhibits Notch signaling at different stages of retinal organoid differentiation to enhance photoreceptor specification, showing increased cone and rod markers at specific timepoints.
Investigative Ophthalmology & Visual Science · Sep 21, 2022Peer-reviewedDevelopmental Biology