Author

David E. O. Van Hoofstat

ORCID 0000-0002-2209-3063Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Assay:DNA methylation· 2 Research Focus:variant calling· 2 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Dieter L. D. DeforceiD· 2 shared Filip Van NieuwerburghiD· 2 shared Liesl De KeyzeriD· 2 shared Sonja ŠkeviniD· 2 shared Koen DeserrannoiD· 1 shared Lynn De Waele· 1 shared Olivier TytgatiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 19 mutual co-author links

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2 shared papersBiochemistry

Dieter L. D. DeforceORCID

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2 papers

Recent·Most cited

Recombinase polymerase amplification: characterization and mitigation of undescribed multimeric artefacts

Liesl De Keyzer, Koen Deserranno, Sonja Škevin, David E. O. Van Hoofstat, Dieter L. D. Deforce, Filip Van Nieuwerburgh

This study characterizes multimeric artefacts in RPA and identifies temperature and T4 UvsX concentration as ways to reduce them.

bioRxiv · Aug 21, 2026 · PreprintBiochemistry

Recombinase Polymerase Amplification of Forensic Short Tandem Repeat Loci

Sonja Škevin, Liesl De Keyzer, Lynn De Waele, Olivier Tytgat, David E. O. Van Hoofstat, Dieter L. D. Deforce, Filip Van Nieuwerburgh

This study evaluates Recombinase Polymerase Amplification (RPA) for amplifying forensic STR loci, showing successful singleplex amplification but challenges in multiplex formats.

Scientific Reports · Nov 18, 2025Peer-reviewedGenomics