Molecular BiologyJournal of the American Heart AssociationPeer-reviewed
Mineralocorticoid Receptor Antagonism Reduces Atrial Arrhythmias Post-Cardiac Surgery and Attenuates Atrial Stress Responses to Cardioplegic Arrest
Sina Danesh, Fazal Wahab Khan, Trevor C. Chopko…·Paul C. Y. Tang
This study shows preoperative MRA use reduces new-onset POAF and long-standing AF development, with canrenone suppressing MR target genes linked to chronic AF in atrial cardiomyocytes during cold preservation.
7 citationstop 4%