Author

J. Pedro Safi

Mayo ClinicORCID 0000-0002-8666-0151Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Aurora LeeiD· 1 shared Austin Todd· 1 shared Bertram PittiD· 1 shared Fazal Wahab KhaniD· 1 shared Francis D. PaganiiD· 1 shared Hakan OraliD· 1 shared Hartzell Vernon SchaffiD· 1 shared Ienglam LeiiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Aurora LeeORCID

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1 paper

Recent·Most cited

Mineralocorticoid Receptor Antagonism Reduces Atrial Arrhythmias Post-Cardiac Surgery and Attenuates Atrial Stress Responses to Cardioplegic Arrest

Sina Danesh, Fazal Wahab Khan, Trevor C. Chopko, Aurora Lee, Ran Huo, Shuyang Lu, Vincy Tam, J. Pedro Safi, Wenbin Gao, Austin Todd, Francis D. Pagani, Joseph John Maleszewski, Hartzell Vernon Schaff, Paul A. Friedman, Hakan Oral, , Paul C. Y. Tang

This study shows preoperative MRA use reduces new-onset POAF and long-standing AF development, with canrenone suppressing MR target genes linked to chronic AF in atrial cardiomyocytes during cold preservation.

Journal of the American Heart Association · Oct 9, 2025Peer-reviewedMolecular Biology