Author

Ienglam Lei

Mayo ClinicORCID 0000-0002-0248-6871Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Biochemistry· 1 Developmental Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:ATAC-seq· 1 Research Focus:cell-cell communication· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

Paul C. Y. TangiD· 2 shared Andrew J. PerciaccanteiD· 1 shared Aurora LeeiD· 1 shared Austin Todd· 1 shared Bertram PittiD· 1 shared Emily A. ChapmaniD· 1 shared Fazal Wahab KhaniD· 1 shared Francis D. PaganiiD· 1 shared

Activity by Year

2020-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMolecular Biology

Paul C. Y. TangORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Mineralocorticoid Receptor Antagonism Reduces Atrial Arrhythmias Post-Cardiac Surgery and Attenuates Atrial Stress Responses to Cardioplegic Arrest

Sina Danesh, Fazal Wahab Khan, Trevor C. Chopko, Aurora Lee, Ran Huo, Shuyang Lu, Vincy Tam, J. Pedro Safi, Wenbin Gao, Austin Todd, Francis D. Pagani, Joseph John Maleszewski, Hartzell Vernon Schaff, Paul A. Friedman, Hakan Oral, , Paul C. Y. Tang

This study shows preoperative MRA use reduces new-onset POAF and long-standing AF development, with canrenone suppressing MR target genes linked to chronic AF in atrial cardiomyocytes during cold preservation.

Journal of the American Heart Association · Oct 9, 2025Peer-reviewedMolecular Biology

Extracellular Matrix Alterations in Chronic Ischemic Cardiomyopathy Revealed by Quantitative Proteomics

Kevin M. Buck, Holden T. Rogers, Zachery R. Gregorich, Morgan W. Mann, Timothy J. Aballo, Zhan Gao, Emily A. Chapman, Andrew J. Perciaccante, Scott J. Price, Ienglam Lei, Paul C. Y. Tang, Ying Ge

This study uses quantitative proteomics to identify ECM protein alterations in end-stage ICM, revealing key upregulated components and pathways involved in adverse remodeling.

JCI Insight · Sep 30, 2025Peer-reviewedBiochemistry

SWI/SNF component BAF250a coordinates OCT4 and WNT signaling pathway to control cardiac lineage differentiation

Ienglam Lei, Shuo Tian, Victor Chen, Yong Bo Zhao, Zhong Wang

This study shows BAF250a facilitates cardiac differentiation by enabling OCT4 and β-catenin interaction, affecting gene expression and cell cycle progression in human ESCs.

Frontiers in Cell and Developmental Biology · Jan 22, 2020Peer-reviewedDevelopmental Biology