Author

Jeff Soules

Flatiron InstituteORCID 0000-0002-2240-1038Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 2 Assay:cryo-EM· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

Aaditya V. RanganiD· 1 shared Alessio Paolo BuccinoiD· 1 shared Alison E. ComrieiD· 1 shared Andrew TrittiD· 1 shared Caleb T. KemereiD· 1 shared Chris BrozdowskiiD· 1 shared Cristofer HolobetziD· 1 shared Daniel P. GramlingiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperBiophysics

Aaditya V. RanganORCID

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2 papers

Recent·Most cited

CryoLike: A python package for cryo-electron microscopy image-to-structure likelihood calculations

Wai Shing Tang, Jeff Soules, Aaditya V. Rangan, Pilar Cossio

CryoLike evaluates image-to-structure likelihoods for cryo-EM data using Fourier-Bessel representations to improve computational efficiency.

Acta Crystallographica Section D Structural Biology · Nov 12, 2025Peer-reviewedBiophysics

Spyglass: a framework for reproducible and shareable neuroscience research

Kyu Hyun Lee, Eric L. Denovellis, Ryan Ly, Jeremy F. Magland, Jeff Soules, Alison E. Comrie, Daniel P. Gramling, Jennifer A. Guidera, Rhino Nevers, Philip Adenekan, Chris Brozdowski, Samuel R. Bray, Emily J. Monroe, Ji Hyun Bak, Michael E. Coulter, , Loren M. Frank

Spyglass provides a reproducible and shareable framework for neuroscience research, enabling data reuse and analysis across labs using standardized formats and pipelines.

bioRxiv · Jan 25, 2024 · PreprintNeuroscience